What is Kratom?
Kratom a Southeast Asian plant best-known for its opiate-like effects, might put users in danger of addiction and even death, the United States Food and Drug Administration said in a public health advisory today. The drug has been rising in quality as an opioid alternative.
Kratom, which has been consumed in southeast asia for hundreds of years, binds to the same opioid receptor as painkiller, so it can treat pain. Some chemists figure it’s a promising start line for new, less addictive painkillers. However it’s presently taken as a recreational drug, with its users saying it treats anxiety, depression and opioid withdrawal. These anecdotal reports aren’t a similar as real medical analysis and more is needed to determine the plant’s medical advantages. At a time when we have hit a critical point in the opioid epidemic, the Food and Drug Administration statement said, the increasing use of kratom as an alternative or adjunct to opioid use is extremely concerning.
The potential safety risks for kratom raise significant issues, according to the Food and Drug Administration. The Food and Drug Administration is conscious of 36 deaths connected to the use of products containing kratom. Calls to poison management centers concerning kratom have multiplied 10-fold from 2010 to 2015.
How Kratom Works
Kratom targets an area of the brain that responds to medicine like morphine, codeine, and Fentanyl, according to a study revealed earlier this month by Susruta Majumdar, PhD, a research worker at Memorial Sloan Kettering Cancer Center in new york. These kinds of drugs are known as opioids.
Majumdar’s study found that unlike morphine, a synthetic compound derived from kratom (mitragynine pseudoindoxyl) doesn’t cause harmful side effects like slowed breathing known as respiratory depression constipation, and physical dependence. Since most deaths from opioid overdose are because of respiratory depression, he believes kratom merits further study to check if some of its compounds will be harnessed for medical advantages that are potentially less addictive.
Whether kratom can eventually be prohibited, however, depends on the Drug Enforcement Administration. The Drug Enforcement Administration can review the FDA’s assessment and create a determination, says Drug Enforcement Administration representative Wade Sparks.